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Trans-Nerolidol is a sesquiterpene and naturally produced in plants to protect against insect

Its woody, floral fragrance makes it a viable compound for tea tree oil, lotions and perfumes.

Nerolidol is recognized for its sedative effects and can enhance the drug delivery process through skin.

Nerolidol has the ability to calm anxiety. Studies suggest that in future it may play a role in cannabis’ calming abilities.

Nerolidol contains antioxidants, antibacterial and antimicrobial properties, making it highly valuable for cosmetic and skincare products

About Trans-Nerolidol

Nerolidol is a sesquiterpene (a class of terpenes that contain three isoprene units). It is naturally produced by plants to shield against insects. It is found in two distinct molecular structures - trans-nerolidol and the cis-nerolidol – and the term nerolidol can be referred to both.

Nerolidol has a woody and floral scent with a pinch of citrus and melon. It is commonly found in plants like jasmine, neroli lemongrass, tea tree, lavender and cannabis. Its unique scent and therapeutic properties do make it a vital compound for skincare and cosmetic products. Additionally, Trans-Nerolidol is used as a secret ingredient to flavor food products.

Strains Rich In Nerolidol

Sour Kush

Skywalker OG


Sweet Skunk





Plants high in Trans Nerolidol




Tea Tree



Medical Benefits of Trans-Nerolidol

Despite potential therapeutic uses, trans-nerolidol still needs more clinical trials to uncover and understand the complete medical benefits of terpene. So far, research have concluded the following benefits:

  • Anti-fungal properties – Numerous evidence highlights the efficiency of Nerolidol in exhibiting anti-fungal activity.

  • Antioxidant – Nerolidol can provide protection against oxidative stress and can be used to treat neurological conditions.

  • Sedative and Anti-Anxiety – Nerolidol incorporate calming, sleeping aid properties which can be a useful compound for anti-anxiety effect.

  • Antibacterial and antimicrobial – The antimicrobial agents of Nerolidol have the potential to make certain bacteria more vulnerable to antibiotics, particularly malaria when combined with other drugs.

  • Anti - Cancer properties – In 2017, it was found that Trans Nerolidol can prevent cell growth in human liver cancer and induce cell death.

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