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Also known as the pepper terpene

Caryophyllene has strong anti-inflammatory, antibacterial, antimicrobial, and antioxidant properties.

Its effects could be helpful for a range of conditions like arthritis and nerve pain.

Caryophyllene is a highly researched, complex terpene that bonds cannabinoids with other compounds.

Caryophyllene has a warm, woody, and spicy aroma, similar to black pepper, cinnamon, and cloves.

Caryophyllene is researched for its ability to bind to CB2 receptors.

What is Caryophyllene? 

Caryophyllene, also known as beta-caryophyllene, is an intriguing and rare terpene broadly researched for its ability to bind to CB2 receptors. 

Medical experts find its relationship with our endocannabinoid system quite fascinating. Due to this, Caryophyllene is known for numerous potential medical benefits, particularly Oxidative Stress and Neuroinflammation. 

Caryophyllene structure contains Cyclobutane ring – which is rare in nature and is not found in the rest of the cannabis terpene. It is a more prominent molecule than myrcene and limonene.

Neuroprotective Effects of Caryophyllene

The endocannabinoid system in the human body comprises a vast network of receptors. CB1 renders in the brain whereas CB2 receptors are mainly found in our peripheral organs.

A detailed study highlights that beta-caryophyllene is an agonist of CB2 receptors. In simple language, beta-caryophyllene activates the receptor just like an endogenous signal. CB2 receptors in our nervous system trail the sensation of pain.

Activation of CB2 could suppress reactive microglia behavior, and further may help to support neuron health. In addition, it can demonstrate a protective role in neuroinflammatory conditions.

High-caryophyllene cannabis strains


Bubba Kush

Sour Diesel



Original Glue

Cookies and Cream


The White Master Kush

Death Star

What are caryophyllene properties?

Caryophyllene has a wide variety of therapeutic potential, but it is mainly recommended for pain-relieving properties.


Caryophyllene has antioxidant and anti-inflammatory properties, making it a highly possible terpene for treating inflammatory bowel disease. Further ongoing research reveals that caryophyllene, in the near future, can be used to treat anxiety and depression.

  • Caryophyllene can reduce brain inflammation and chemicals that cause oxidative stress. 

  • Caryophyllene has Antibacterial & Antimicrobial Properties; which helps fight bacterial dental plaque and is a potential alternative against microorganisms like influenza. 

  • β-caryophyllene is also known for its therapeutic properties and can treat Osteoporosis.

  • Caryophyllene can be used in combination with an anti-cancer agent such as paclitaxel.

What are caryophyllene properties?

Beta-caryophyllene, also called b-caryophyllene or BCP, is the most common appearance of this terpene in cannabis and food. This terpene binds directly with your CB2 receptor and is consumed as a dietary cannabinoid.

  • Caryophyllene may Increase Mitochondrial Function, contributing to long life. 

  • Safeguards the brain from neuroinflammation

  • Caryophyllene Improve Stroke Outcome; minimizes swelling or neuronal damage. 

  • Caryophyllene can reduce high levels of cholesterol & protects the vascular system. 

  • Caryophyllene can bypass the blood-brain barrier, prevent Alzheimer’s disease, and alleviate cognitive dysfunction. 

  • Caryophyllene can be used to reduce/treat depression and anxiety

  • BCP discharges chronic pain and neuropathy.

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